some weapon mods seem pointless compared to the alternative

[methy]

Honestly the frag grenade can be very useful against a group of enemies, and sometimes I even use it to weaken Mancubus.

But the Syphon? My god that thing is so broken. On my UN run, once I got Syphon the game got a LOT easier, that thing makes you invicible, especially if used with the Increased Weapon Power Rune and it drains Armor as well. Not to mention that you can keep grinding health and armor against even a mere Possessed until you're at max.